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1

C–H activations on a 1H-1,4-benzodiazepin-2(3H)-one template

John Spencer, Babur Z. Chowdhry, Anthony I. Mallet, Rajendra P. Rathnam, Trushar Adatia, Alan Bashall, Frank Rominger

Journal:

Year:

2008

Language:

english

File:

PDF, 505 KB

english, 2008

2

Microwave mediated reduction of heterocycle and fluorine containing nitroaromatics with Mo(CO)6 and DBU

John Spencer, Rajendra P. Rathnam, Hiren Patel, Nazira Anjum

Journal:

Year:

2008

Language:

english

File:

PDF, 776 KB

english, 2008

3

Synthesis and biological evaluation of 1,4-benzodiazepin-2-ones with antitrypanosomal activity

John Spencer, Rajendra P. Rathnam, Alan L. Harvey, Carol J. Clements, Rachel L. Clark, Michael P. Barrett, Pui Ee Wong, Louise Male, Simon J. Coles, Simon P. Mackay

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 883 KB

english, 2011

4

Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity

Spencer, John, Rathnam, Rajendra P., Motukuri, Mahesh, Kotha, Arun K., Richardson, Simon C. W., Hazrati, Ali, Hartley, John A., Male, Louise, Hursthouse, Michael B.

Journal:

Dalton Transactions

Year:

2009

Language:

english

File:

PDF, 279 KB

english, 2009

5

Excellent correlation between cathepsin B inhibition and cytotoxicity for a series of palladacycles

Spencer, John, Casini, Angela, Zava, Olivier, Rathnam, Rajendra P., Velhanda, Santosh K., Pfeffer, Michel, Callear, Samantha K., Hursthouse, Michael B., Dyson, Paul J.

Journal:

Dalton Transactions

Year:

2009

Language:

english

File:

PDF, 308 KB

english, 2009

6

Identification and development of the 1,4-benzodiazepin-2-one and quinazoline-2,4-dione scaffolds as submicromolar inhibitors of HAT

Rachel L. Clark, Carol J. Clements, Michael P. Barrett, Simon P. Mackay, Rajendra P. Rathnam, George Owusu-Dapaah, John Spencer, Judith K. Huggan

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 515 KB

english, 2012

7

1,4-benzodiazepin-2-ones in medicinal chemistry

Spencer, John, Rathnam, Rajendra P, Chowdhry, Babur Z

Journal:

Future Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.18 MB

english, 2010

8

Comparison of the safety information on drug labels in three developed countries: The USA, UK and Canada

Alshammari, Thamir M., Devadasu, Venkat Ratnam, Rathnam, Rajendra Prasad

Journal:

Saudi Pharmaceutical Journal

Year:

2017

Language:

english

File:

PDF, 363 KB

english, 2017